Quinolones News

#2 September 10, 2010

Review of treatments for MDR and XDR tuberculosis recommends high-dose levofloxacin

A review of the treatment of multidrug-resistant (MDR) and extensively drug resistant (XDR) tuberculosis cites a number of treatment options based on efficacy, safety and cost. Following isoniazid, pyrazinamide and ethambutol are the fluoroquinolones with high-dose levofloxacin as the first choice in this group. Less recommended drugs include injectables, like capreomycin, second-line drugs, like thioamides, and a fifth group including carbapenems.

PMID: 20797644

Lancet Infect Dis. 2010 Sep;10(9):621-629.

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