Question 5

What are the PK/PD features of levofloxacin in special patient populations- for example, critically ill patients, elderly or those with renal impairment?

The pharmacologic profile of levofloxacin remains remarkably stable across a wide range of different patient subgroups. However, due to its renal excretion, it may need to be modified in patients with very reduced renal function. Generally, levofloxacin is very safe in a wide range of patient populations.