Medical Updates | Infection Update

MEDICAL UPDATES

Oral sitafloxacin vs intravenous ceftriaxone for the treatment of acute pyelonephritis and complicated urinary tract infection

An open-label randomised, controlled, noninferiority clinical trial has shown that oral sitafloxacin is noninferior to intravenous (IV) ceftriaxone followed by oral cefdinir for the treatment of acute pyelonephritis and complicated...

An open-label randomised, controlled, noninferiority clinical trial has shown that oral sitafloxacin is noninferior to intravenous (IV) ceftriaxone followed by oral cefdinir for the treatment of acute pyelonephritis and complicated...

Levofloxacin remains as one of the core agents in the treatment of tuberculosis

According to the current World Health Organization (WHO) guidelines (2016 update), fluoroquinolones including moxifloxacin, gatifloxacin, and levofloxacin are important second-line anti-tuberculosis (anti-TB) agents.1 A review of existing literature conducted by...

According to the current World Health Organization (WHO) guidelines (2016 update), fluoroquinolones including moxifloxacin, gatifloxacin, and levofloxacin are important second-line anti-tuberculosis (anti-TB) agents.1 A review of existing literature conducted by...

Oral levofloxacin and intravenous vancomycin for bacteraemia due to Microbacterium paraoxydans

A patient with bacteraemia associated with a long-term central venous catheter (CVC) due to Microbacterium paraoxydans responded well to replacement of CVC, and treatment with oral levofloxacin and intravenous vancomycin....

A patient with bacteraemia associated with a long-term central venous catheter (CVC) due to Microbacterium paraoxydans responded well to replacement of CVC, and treatment with oral levofloxacin and intravenous vancomycin....

Levofloxacin for lower lobe pneumonia presenting as persistent hiccups

Levofloxacin has been shown to resolve a case of community-acquired pneumonia in an elderly patient presenting with persistent hiccups – without any typical symptoms, signs, or laboratory findings of pneumonia....

Levofloxacin has been shown to resolve a case of community-acquired pneumonia in an elderly patient presenting with persistent hiccups – without any typical symptoms, signs, or laboratory findings of pneumonia....

Oral sitafloxacin as a switch therapy for the treatment of non-bacteraemic acute pyelonephritis

21 February, 2019

A treatment regimen of carbapenem followed by sitafloxacin or ertapenem was found to be effective in patients with non-bacteraemic acute pyelonephritis caused by extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC). The incidence...

A treatment regimen of carbapenem followed by sitafloxacin or ertapenem was found to be effective in patients with non-bacteraemic acute pyelonephritis caused by extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC). The incidence...

Managing mycobacterial infection after lung transplantation with levofloxacin: Case series

11 February, 2019

The combination of levofloxacin with isoniazid, pyrazinamide and ethambutol was found to be effective in managing mycobacterial infection in lung transplant recipients. The risk of mycobacterial infection is high for...

The combination of levofloxacin with isoniazid, pyrazinamide and ethambutol was found to be effective in managing mycobacterial infection in lung transplant recipients. The risk of mycobacterial infection is high for...

Levofloxacin improves spondylitis complication in Escherichia coli endocarditis

18 January, 2019

A two-month course of levofloxacin (500 mg/day) resolved purulent spondylitis in a patient with Escherichia coli infective endocarditis (IE). A 58-year old Japanese woman presented with febrile illness, malaise, and...

A two-month course of levofloxacin (500 mg/day) resolved purulent spondylitis in a patient with Escherichia coli infective endocarditis (IE). A 58-year old Japanese woman presented with febrile illness, malaise, and...

Ceftriaxone plus levofloxacin for the treatment of Streptococcus intermedius pleuropulmonary infection

11 January, 2019

Ceftriaxone–levofloxacin combination is the most frequently used antimicrobial for the treatment of Streptococcus intermedius pleuropulmonary infection; drainage of pleural effusion and other surgical procedures such as pleurectomy, thoracotomy, decortication, and...

Ceftriaxone–levofloxacin combination is the most frequently used antimicrobial for the treatment of Streptococcus intermedius pleuropulmonary infection; drainage of pleural effusion and other surgical procedures such as pleurectomy, thoracotomy, decortication, and...

Sitafloxacin as part of intermittent maintenance therapy prevents recurrence of Mycobacterium avium complex lung disease

05 January, 2019

Intermittent maintenance therapy (IMT) that includes sitafloxacin has demonstrated positive treatment outcomes in patients treated successfully for Mycobacterium avium complex lung disease (MAC-LD) – suggesting the effectiveness of IMT for...

Intermittent maintenance therapy (IMT) that includes sitafloxacin has demonstrated positive treatment outcomes in patients treated successfully for Mycobacterium avium complex lung disease (MAC-LD) – suggesting the effectiveness of IMT for...

Oral levofloxacin for the treatment of tracheobronchitis in a laryngectomee due to nontypeable Haemophilus influenzae

26 December, 2018

Oral levofloxacin was found to be effective for the treatment of beta-lactamase-producing nontypeable Haemophilus influenzae infection in a laryngectomee. A 76-year-old Caucasian man presented with fever, sputum production and purulent...

Oral levofloxacin was found to be effective for the treatment of beta-lactamase-producing nontypeable Haemophilus influenzae infection in a laryngectomee. A 76-year-old Caucasian man presented with fever, sputum production and purulent...

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