Medical Updates | Infection Update

MEDICAL UPDATES

Inhaled levofloxacin liposomes complemented with lysozyme: An effective antimicrobial and antibiofilm strategy against Staphylococcus aureus lung infection

Staphylococcus aureus is a Gram-positive organism that is responsible for various infections such as skin abscess, osteomyelitis, and lung infection among patients with cystic fibrosis and chronic obstructive pulmonary disease...

Staphylococcus aureus is a Gram-positive organism that is responsible for various infections such as skin abscess, osteomyelitis, and lung infection among patients with cystic fibrosis and chronic obstructive pulmonary disease...

Fluoroquinolones such as levofloxacin show promise as an alternative monotherapy for Pseudomonas aeruginosa bacteraemia

Pseudomonas aeruginosa is a Gram-negative organism that confers a high mortality risk, especially in cases of bloodstream infection or bacteraemia.1-3 The most common sources of bacteraemia include pneumonia, intra-abdominal infections,...

Pseudomonas aeruginosa is a Gram-negative organism that confers a high mortality risk, especially in cases of bloodstream infection or bacteraemia.1-3 The most common sources of bacteraemia include pneumonia, intra-abdominal infections,...

Sitafloxacin Demonstrates Excellent Activity Against Ciprofloxacin-Resistant Neisseria gonorrhoeae Isolates

Neisseria gonorrhoeae is a sexually-transmitted pathogen that may cause asymptomatic infection or may clinically present as urethritis, cervicitis, pharyngitis or proctitis.1 In women, untreated gonorrhoea may cause long-term abdominal pain,...

Neisseria gonorrhoeae is a sexually-transmitted pathogen that may cause asymptomatic infection or may clinically present as urethritis, cervicitis, pharyngitis or proctitis.1 In women, untreated gonorrhoea may cause long-term abdominal pain,...

Sitafloxacin demonstrates excellent in vitro activity against a global panel of antimicrobial-resistant and multidrug-resistant Neisseria gonorrhoeae

The World Health Organization (WHO) estimated in 2012 that 78 million new cases of urogenital gonorrhoea occur among adults annually.1 The emergence of N. gonorrhoeae resistant to ceftriaxone, the empiric...

The World Health Organization (WHO) estimated in 2012 that 78 million new cases of urogenital gonorrhoea occur among adults annually.1 The emergence of N. gonorrhoeae resistant to ceftriaxone, the empiric...

Levoﬂoxacin-loaded chitosan nanoparticle formulation improves ocular delivery and antimicrobial activity against Pseudomonas aeruginosa and Staphylococcus aureus

Ophthalmologic infections can be challenging to treat because of the relative impermeability of the cornea. It is estimated that only 1% to 5% of the applied topical antibiotic penetrates into...

Ophthalmologic infections can be challenging to treat because of the relative impermeability of the cornea. It is estimated that only 1% to 5% of the applied topical antibiotic penetrates into...

Research and Development of Quinolones in Daiichi Sankyo Co., Ltd.

Shogo Atarashi, PhD Senior Advisor, Marketing Department, ASCA Company, Daiichi Sankyo Co., Ltd., Tokyo, Japan Quinolones, which are antimicrobials first launched in the 1960s, have exhibited expanded significance in the...

Shogo Atarashi, PhD Senior Advisor, Marketing Department, ASCA Company, Daiichi Sankyo Co., Ltd., Tokyo, Japan Quinolones, which are antimicrobials first launched in the 1960s, have exhibited expanded significance in the...

Combination Regimens using Beta-lactam plus a Macrolide or Fluoroquinolone Continue to Provide Optimal Therapy in CAP patients

14 February, 2018

Patients around the world continue to present with community-acquired pneumonia (CAP), often requiring hospitalization, and associated with a significant economic burden. While combination therapy is recommended in most international guidelines,...

Patients around the world continue to present with community-acquired pneumonia (CAP), often requiring hospitalization, and associated with a significant economic burden. While combination therapy is recommended in most international guidelines,...

Levofloxacin plus Colistin Exhibit Synergistic Activity against Acinetobacter baumannii

15 January, 2018

Primarily responsible for nosocomial infections, Acinetobacter baumanniihas become a challenging pathogen to treat, with multi-drug resistant strains (MDR-AB) now widespread. Polymixins and tigecycline have been the usual first line treatment, however...

Primarily responsible for nosocomial infections, Acinetobacter baumanniihas become a challenging pathogen to treat, with multi-drug resistant strains (MDR-AB) now widespread. Polymixins and tigecycline have been the usual first line treatment, however...

WHO Priority List for Developing New Antibiotics in the Era of Bacterial Resistance

15 January, 2018

The rise of antibiotic-resistant bacteria has been a global health problem for many years, but despite this, there have been no major advances in the development of new antimicrobial agents...

The rise of antibiotic-resistant bacteria has been a global health problem for many years, but despite this, there have been no major advances in the development of new antimicrobial agents...

Sitafloxacin-Containing Triple Regimen Effective for Eradicating Helicobacter pylori in Patients with Penicillin Allergy

24 November, 2017

Antibiotic regimens to eradicate Helicobacter pylori (H. pylori) have been developed for most patient subgroups, however they have not been standardized for patients with a penicillin allergy, which reportedly occurs in 1-12%...

Antibiotic regimens to eradicate Helicobacter pylori (H. pylori) have been developed for most patient subgroups, however they have not been standardized for patients with a penicillin allergy, which reportedly occurs in 1-12%...

POPULAR ARTICLES