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Can COPD predispose a patient to severe COVID-19 infection?

The severity of COVID-19 illness caused by SARS-CoV-2 may extend from asymptomatic infection or mild self-limiting upper respiratory tract illness, to severe pneumonia with respiratory failure, or death.1 The presence...

The severity of COVID-19 illness caused by SARS-CoV-2 may extend from asymptomatic infection or mild self-limiting upper respiratory tract illness, to severe pneumonia with respiratory failure, or death.1 The presence...

Saliva as a diagnostic tool for asymptomatic SARS-CoV-2 infection

Accurate and rapid testing of SARS-CoV-2 infection is key to timely management of symptoms and prevention of disease transmission. Real-time RT-PCR (rRT-PCR) performed using nasopharyngeal and respiratory specimens are the...

Accurate and rapid testing of SARS-CoV-2 infection is key to timely management of symptoms and prevention of disease transmission. Real-time RT-PCR (rRT-PCR) performed using nasopharyngeal and respiratory specimens are the...

Nanotechnology to combat COVID-19 infections

The COVID-19 pandemic has had an indelible effect, with at least 517,779,437 cases and 6,278,165 related deaths reported globally.1 Despite substantial multi-disciplinary research efforts to combat SARS-CoV-2, there is a...

The COVID-19 pandemic has had an indelible effect, with at least 517,779,437 cases and 6,278,165 related deaths reported globally.1 Despite substantial multi-disciplinary research efforts to combat SARS-CoV-2, there is a...

Age-linked variations in UTI pathogens and antibiotic resistance patterns may guide empirical antimicrobial treatment

Urinary tract infections (UTIs) are one of the most common reasons for hospital visits worldwide and are associated with significant economic burden.1-3 In the United States alone, an estimated 2.8...

Urinary tract infections (UTIs) are one of the most common reasons for hospital visits worldwide and are associated with significant economic burden.1-3 In the United States alone, an estimated 2.8...

Colchicine does not prevent mechanical ventilation or reduce mortality risk in COVID-19 hospitalisations

Mortality rates among COVID-19-linked hospitalisations stand at a reported 17.1%,1 which is markedly above the global COVID-19 mortality rate of 1.3%, as calculated based on the current global data on...

Mortality rates among COVID-19-linked hospitalisations stand at a reported 17.1%,1 which is markedly above the global COVID-19 mortality rate of 1.3%, as calculated based on the current global data on...

Helicobacter pylori infections: A review of the current standard of care

16 February, 2022

In 2015, approximately 4.4 billion Helicobacter pylori infections were reported worldwide.1 Prevalence of H. pylori infections varies across countries, with more industrialised countries showing a plateau or decline in infection...

In 2015, approximately 4.4 billion Helicobacter pylori infections were reported worldwide.1 Prevalence of H. pylori infections varies across countries, with more industrialised countries showing a plateau or decline in infection...

A combination of prior infection and vaccination confers the strongest immune response against COVID-19 variants

12 January, 2022

Variants of SARS-CoV-2, the virus causing COVID-19, are constantly emerging and will likely continue to, driven by community carriers.1 Immunity to the virus is attained through vaccination or prior infection,...

Variants of SARS-CoV-2, the virus causing COVID-19, are constantly emerging and will likely continue to, driven by community carriers.1 Immunity to the virus is attained through vaccination or prior infection,...

Antimicrobial treatment of urinary tract infection with temocillin shows reduced selection for resistant gut bacteria compared with cefotaxime

14 December, 2021

Cefotaxime, a broad-spectrum antibiotic, also effective against certain multiresistant strains, is currently used to treat febrile urinary tract infections (UTIs).1 Failure of cefotaxime (and other third-generation cephalosporins) due to reduced...

Cefotaxime, a broad-spectrum antibiotic, also effective against certain multiresistant strains, is currently used to treat febrile urinary tract infections (UTIs).1 Failure of cefotaxime (and other third-generation cephalosporins) due to reduced...

Localised vancomycin delivery via microneedle arrays reduces methicillin-resistant Staphylococcus aureus growth on skin

12 November, 2021

Skin and soft-tissue infections (SSTI) are a common type of bacterial infection, making up almost 10% of annual hospitalisations.1 Staphylococcus aureus is the causative agent in most cases of SSTIs,...

Skin and soft-tissue infections (SSTI) are a common type of bacterial infection, making up almost 10% of annual hospitalisations.1 Staphylococcus aureus is the causative agent in most cases of SSTIs,...

High viral abundance in lungs and low immune response to SARS-CoV-2 predicts mortality

19 October, 2021

Factors associated with COVID-19 mortality include age, obesity, the need for mechanical ventilation following respiratory failure, and certain comorbidities.1,2 Recent research has also suggested that features of the lung microbiome...

Factors associated with COVID-19 mortality include age, obesity, the need for mechanical ventilation following respiratory failure, and certain comorbidities.1,2 Recent research has also suggested that features of the lung microbiome...

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