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To what extent does COVID-19 bacterial co-infection impact clinical outcomes?

COVID-19, caused by the SARS-CoV-2 virus, has resulted in over 6.8 million deaths worldwide.1 Risk factors associated with severe COVID-19 disease symptoms include advanced age, male sex and comorbidities.2 Although...

COVID-19, caused by the SARS-CoV-2 virus, has resulted in over 6.8 million deaths worldwide.1 Risk factors associated with severe COVID-19 disease symptoms include advanced age, male sex and comorbidities.2 Although...

The role of bivalent booster COVID-19 vaccinations in the fight against SARS-CoV-2 Omicron infection

The currently circulating SARS-CoV-2 Omicron BA.1 subvariant consists of more than 30 mutations in the spike protein, of which at least 15 mutations have been identified in the receptor-binding domain,...

The currently circulating SARS-CoV-2 Omicron BA.1 subvariant consists of more than 30 mutations in the spike protein, of which at least 15 mutations have been identified in the receptor-binding domain,...

Immune evasion properties of SARS-CoV-2 Omicron BQ and XBB subvariants – a potential global threat

03 February, 2023

The COVID-19 pandemic remains a significant global concern owing to the emergence of the Omicron variants and its descendant subvariants.1,2,3 Evidence suggests that the increasing prevalence and rapidly expanding spike...

The COVID-19 pandemic remains a significant global concern owing to the emergence of the Omicron variants and its descendant subvariants.1,2,3 Evidence suggests that the increasing prevalence and rapidly expanding spike...

What is the safety profile of a second COVID-19 mRNA vaccine booster?

22 December, 2022

The emergence of SARS-CoV-2 variants of concern (VoCs), and the eventual waning efficacy of the primary vaccination series and first booster dose indicated a need for a second booster dose...

The emergence of SARS-CoV-2 variants of concern (VoCs), and the eventual waning efficacy of the primary vaccination series and first booster dose indicated a need for a second booster dose...

How effective is a recombinant plant-based COVID-19 vaccine?

04 November, 2022

As reported by the World Health Organization, the ongoing COVID-19 pandemic infected more than 608 million people and resulted in 6.5 million deaths worldwide.1 Despite successful deployment of numerous SARS-CoV-2...

As reported by the World Health Organization, the ongoing COVID-19 pandemic infected more than 608 million people and resulted in 6.5 million deaths worldwide.1 Despite successful deployment of numerous SARS-CoV-2...

Can maternal vaccination protect infants against COVID-19 related hospitalization?

13 September, 2022

The risk of severe illness and hospitalization associated with COVID-19 is reportedly higher in infants who are 6 months of age or younger;1,2 however, no vaccines are currently authorized for...

The risk of severe illness and hospitalization associated with COVID-19 is reportedly higher in infants who are 6 months of age or younger;1,2 however, no vaccines are currently authorized for...

Can COPD predispose a patient to severe COVID-19 infection?

The severity of COVID-19 illness caused by SARS-CoV-2 may extend from asymptomatic infection or mild self-limiting upper respiratory tract illness, to severe pneumonia with respiratory failure, or death.1 The presence...

The severity of COVID-19 illness caused by SARS-CoV-2 may extend from asymptomatic infection or mild self-limiting upper respiratory tract illness, to severe pneumonia with respiratory failure, or death.1 The presence...

Saliva as a diagnostic tool for asymptomatic SARS-CoV-2 infection

Accurate and rapid testing of SARS-CoV-2 infection is key to timely management of symptoms and prevention of disease transmission. Real-time RT-PCR (rRT-PCR) performed using nasopharyngeal and respiratory specimens are the...

Accurate and rapid testing of SARS-CoV-2 infection is key to timely management of symptoms and prevention of disease transmission. Real-time RT-PCR (rRT-PCR) performed using nasopharyngeal and respiratory specimens are the...

Nanotechnology to combat COVID-19 infections

The COVID-19 pandemic has had an indelible effect, with at least 517,779,437 cases and 6,278,165 related deaths reported globally.1 Despite substantial multi-disciplinary research efforts to combat SARS-CoV-2, there is a...

The COVID-19 pandemic has had an indelible effect, with at least 517,779,437 cases and 6,278,165 related deaths reported globally.1 Despite substantial multi-disciplinary research efforts to combat SARS-CoV-2, there is a...

Age-linked variations in UTI pathogens and antibiotic resistance patterns may guide empirical antimicrobial treatment

Urinary tract infections (UTIs) are one of the most common reasons for hospital visits worldwide and are associated with significant economic burden.1-3 In the United States alone, an estimated 2.8...

Urinary tract infections (UTIs) are one of the most common reasons for hospital visits worldwide and are associated with significant economic burden.1-3 In the United States alone, an estimated 2.8...

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