Optimal Management of RTI – Intriguing New Results in ABECOPD in Asia
Question 16
Could you describe the results in more detail?
There were 407 isolates cultured with the major pathogens being Enterobacteriaceae (41%; 167/407), including Klebsiella spp. (108/407), Enterobacter spp. (22/407) and Escherichia coli (17/407), and other Gram-negative bacilli (25%; 101/407) including 63 isolates of P. aeruginosa and 22 isolates of A. baumannii. S. pneumoniae, H. influenzae and M. catarrhalis were identified in 17.4%, 7.9% and 5.2% of isolates, respectively. Staphylococcus aureus was identified in 3.7% of isolates with one third of these being methicillin-resistant S. aureus (5/15) (Table 2).
Table 2. Rank order of pathogen frequency among bacterial species causing ABECOPD in seven Asian countries
| Rank | Organism | Number | % of total | ||
| 1 | Klebsiella spp. | 108 | 26.5 | ||
| 2 | Haemophilus influenzae | 71 | 17.4 | ||
| 3 | Pseudomonas aeruginosa | 63 | 15.5 | ||
| 4 | Streptococcus pneumoniae | 32 | 7.9 | ||
| 5 | Enterobacter spp. | 22 | 5.4 | ||
| 6 | Acinetobacter baumannii | 22 | 5.4 | ||
| 7 | Moraxella catarrhalis | 21 | 5.2 | ||
| 8 | Escherichia coli | 17 | 4.2 | ||
| 9 | Serratia spp. | 10 | 2.5 | ||
| 10 | Staphylococcus aureus | 10 | 2.5 | ||
| 11 | Stenotrophomonas maltophilia | 7 | 1.7 | ||
| 12 | Proteus spp. | 5 | 1.2 | ||
| 13 | MRSA | 5 | 1.2 | ||
| 14 | Pseudomonas spp. | 3 | 0.7 | ||
| 15 | Acinetobacter spp. | 3 | 0.7 | ||
| 16 | Citrobacter spp. | 2 | 0.5 | ||
| 17 | Pantoea spp. | 2 | 0.5 | ||
| 18 | Alcaligenes xylosoxidans | 2 | 0.5 | ||
| 19 | Kluyvera spp. | 1 | 0.2 | ||
| 20 | Chryseobacterium meningosepticum | 1 | 0.2 | ||
Adapted from reference (16). |
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