Answer 2: Pharmacodynamic parameters: a new paradigm?

20 June, 2018

 

 

 

Yes, this is definitely true. A great deal of insight has been gained in this area over the last 5-10 years (1-4). It is now possible to examine data rationally and quickly to evaluate whether a dose of drug is going to be effective for individual patients, particularly when the causative pathogen and its MIC are known. PD data helps not only to choose the dose and schedule, but also to simultaneously minimize toxicity while also minimizing the emergence of resistance.